Tuesday, May 31, 2011

From pseudogenes to proteins

http://www.nature.com/nmeth/journal/v8/n6/full/nmeth0611-448b.html

Combining proteome analysis with genome sequencing improves gene annotation and yields evidence that some genes presumed to be noncoding are actually expressed.

http://genome.cshlp.org/content/21/5/756

Brosch, M. et al. Shotgun proteomics aids discovery of novel protein-coding genes, alternative splicing and 'resurrected' pseudogenes in the mouse genome. Genome Res. 5, 756767 (2011).

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